Looking for the absolute best pizza in Massachusetts in 2025? Whether you’re a Boston local, visiting the Berkshires, or road-tripping through Cape Cod, this list brings you the top pizza joints locals swear by. These are not just your run-of-the-mill spots — they’re beloved by the community for their crust, sauce, atmosphere, and passion for pizza. As someone who’s spent weekends tasting pies across the Bay State (yes, even in small towns you’ve never heard of), I’ve narrowed it down to 15 must-try pizza places in Massachusetts that consistently deliver perfection.
1. Regina Pizzeria – Boston (North End)
- Location: 11 1/2 Thacher St, Boston, MA
- Known for: Brick oven thin-crust pizza, old-school charm, authentic Italian flavors
- Rating: 4.7/5 (Over 10,000 reviews on Google)
- Website: Regina Pizzeria – Boston (North End)
If there’s one pizza place that screams “Massachusetts institution,” it’s Regina Pizzeria. Opened in 1926, this North End legend is the oldest pizzeria in New England — and arguably still the best. The moment you bite into the crispy, coal-fired crust with their signature tangy tomato sauce and bubbling mozzarella, you’ll understand why people line up around the block.
Must-Try Pizza: Giambotta (loaded with meats & veggies) or the classic Margherita.
2. Santarpio’s Pizza – East Boston
- Location: 111 Chelsea St, East Boston, MA
- Known for: Charred crust, spicy sausage, family-owned vibe
- Rating: 4.6/5
- Website: Santarpio’s Pizza – East Boston
Locals have a serious soft spot for Santarpio’s — and for good reason. This no-frills, cash-only spot has been slinging pies since 1903 and sticks to the “if it ain’t broke, don’t fix it” philosophy. Their sausage pizza is legendary — made with their own homemade sausage grilled right in front of you.
Must-Try Pizza: Sausage, garlic, and hot peppers (classic Santarpio’s combo).
3. Benny’s Pizza – Chicopee
- Location: 412 East St, Chicopee, MA
- Known for: Super cheesy, crunchy crust, huge portions
- Rating: 4.8/5
- Website: Benny’s Pizza – Chicopee
Western Mass doesn’t always get the attention it deserves, but Benny’s Pizza in Chicopee is changing that. This hidden gem has become a local sensation for its over-the-top cheese blends, buttery crust, and insanely satisfying slices. It’s comfort food in the best way.
Must-Try Pizza: Bacon Cheeseburger Pizza — it sounds crazy, but it’s a flavor bomb.
4. Emma’s Pizza – Cambridge (Kendall Square)
- Location: 40 Hampshire St, Cambridge, MA
- Known for: Creative toppings, perfect crust-to-sauce ratio, cozy date-night spot
- Rating: 4.5/5
- Wevsite: Emma’s Pizza – Cambridge (Kendall Square)
Located in the heart of Kendall Square, Emma’s Pizza feels like a cozy retreat with a gourmet twist. Their thin crust is delightfully crisp, and the toppings range from house-roasted garlic to fig and prosciutto. It’s the go-to spot for students, professionals, and anyone who appreciates a carefully crafted pie.
Must-Try Pizza: Caramelized Onion, Gorgonzola & Rosemary Chicken — sweet, savory, and unforgettable.
5. Crust Artisan Pizza – Worcester
- Location: 305 Shrewsbury St, Worcester, MA
- Known for: Wood-fired Neapolitan-style pizza, locally sourced ingredients
- Rating: 4.6/5
- Website: Crust Artisan Pizza – Worcester
Worcester’s food scene has quietly been heating up, and Crust Artisan Pizza is one of its standouts. They bake their pizzas in a wood-fired oven at 800°F, resulting in blistered, chewy crusts that are pure pizza artistry. The menu changes seasonally, keeping things fresh and exciting.
Must-Try Pizza: Mushroom & Truffle Oil — earthy, rich, and elevated.
6. Area Four – Cambridge & Boston
- Locations: 500 Technology Square, Cambridge & 264 East Berkeley St, Boston
- Known for: Fermented dough, bold toppings, hip vibe
- Rating: 4.5/5
- Website: Area Four – Cambridge & Boston
If you’re a fan of pizzas with serious character — chewy, sourdough crusts, fresh mozzarella, and unexpected flavor combos — Area Four is the place to be. Their dough is fermented for over 30 hours, giving it a distinct flavor and texture that pizza nerds love.
Must-Try Pizza: Mushroom & Fontina with truffle oil or the spicy Carnivore (bacon, sausage, soppressata).
7. Flatbread Company – Amesbury
- Location: 5 Market St, Amesbury, MA
- Known for: Organic ingredients, wood-fired pizzas, rustic ambiance
- Rating: 4.7/5
- Website: Flatbread Company – Amesbury
Flatbread Company combines sustainability and pizza in the best way possible. Located in a charming mill-style building, this place serves wood-fired pizzas made with organic ingredients, nitrate-free meats, and farm-fresh veggies.
Must-Try Pizza: Jay’s Heart (a cheesy classic) or the Homemade Sausage pizza.
8. Pepe’s Pizzeria Napoletana – Chestnut Hill
- Location: 199 Boylston St, Chestnut Hill, MA
- Known for: Crispy coal-fired crust, iconic white clam pizza
- Rating: 4.6/5
- Website: Pepe’s Pizzeria Napoletana – Chestnut Hill
Originally from New Haven, CT, Frank Pepe’s has made a big splash in Massachusetts with its Chestnut Hill location. Locals who once made the drive to Connecticut can now enjoy the same coal-fired pies closer to home.
Must-Try Pizza: White Clam Pizza — yes, seafood on pizza, and it’s unbelievably good.
9. Posto – Somerville (Davis Square)
- Location: 187 Elm St, Somerville, MA
- Known for: Authentic Neapolitan pizza, sleek modern setting
- Rating: 4.4/5
- Website: Posto – Somerville (Davis Square)
If you’re craving wood-fired Neapolitan-style pizza with a bit of elegance, Posto delivers. They’re AVPN-certified (which means they meet the gold standard for true Neapolitan pizza) and serve beautifully blistered pies with minimal yet flavorful toppings.
Must-Try Pizza: Margherita D.O.C or the spicy Diavola.
10. Pizzeria Regina – Allston (Harvard Ave)
- Location: 353 Cambridge St, Allston, MA
- Known for: Same original recipe as the North End location, college-friendly vibes
- Rating: 4.5/5
- Website: Pizzeria Regina
Yes, Regina’s again — but this Allston branch deserves its own shoutout. It’s the same iconic pizza from the North End, but with a slightly edgier, more laid-back feel thanks to its proximity to Boston University and the Allston-Brighton music scene.
Must-Try Pizza: Pepperoni and basil — simple but unforgettable.
11. Antonio’s Pizza – Amherst
- Location: 31 N Pleasant St, Amherst, MA
- Known for: Creative slices, college-town energy, massive variety
- Rating: 4.6/5
- Website: Antonio’s Pizza – Amherst
Right in the heart of Amherst’s bustling downtown, Antonio’s Pizza is a local legend — especially among UMass students. You can walk in and grab adventurous slices topped with everything from tortellini to avocado.
Must-Try Pizza: Chicken Bacon Ranch or the Mac & Cheese slice.
12. Otto Pizza – Brookline & Arlington
- Locations: 888 Commonwealth Ave, Brookline & 202 Mass Ave, Arlington
- Known for: Unusual pairings, thin crust, fast service
- Rating: 4.5/5
- Website: Otto Pizza – Brookline & Arlington
Originating in Portland, Maine, Otto Pizza quickly became a Bay State favorite for its quirky yet delicious toppings and reliably crispy crust. Perfect for a quick lunch or takeout.
Must-Try Pizza: Mashed Potato, Bacon & Scallion — sounds weird, tastes heavenly.
13. Al Forno – Providence, RI (Just Outside MA)
- Location: 577 S Main St, Providence, RI (a short drive from SE Massachusetts)
- Known for: Grilled pizza, upscale Italian menu
- Rating: 4.7/5
- Website: Al Forno – Providence, RI (Just Outside MA)
Though not technically in Massachusetts, Al Forno is a bucket-list pizza destination worth the drive from anywhere in the state. Their signature grilled pizza has a lightly charred, smoky flavor you won’t find anywhere else.
Must-Try Pizza: Margarita Grilled Pizza with fresh herbs and romano.
14. Zuma’s Tex-Mex & Pizza – Falmouth (Cape Cod)
- Location: 9 Town Hall Square, Falmouth, MA
- Known for: Tex-Mex meets pizza, cozy coastal vibes
- Rating: 4.4/5
- Website: Zuma’s Tex-Mex & Pizza – Falmouth (Cape Cod)
A quirky little joint in Cape Cod, Zuma’s blends Southwest flavors with traditional pizza, offering up pies that are unique, flavorful, and packed with personality.
Must-Try Pizza: The Taco Pizza or Chicken Fajita Pie — a delicious mashup of two comfort foods.
15. Emma’s Pizza – Cambridge (Kendall Square)
- Location: 40 Hampshire St, Cambridge, MA
- Known for: Ultra-thin crust, modern toppings, artsy vibe
- Rating: 4.5/5
- Website: Emma’s Pizza – Cambridge (Kendall Square)
Tucked away in Kendall Square, Emma’s Pizza is a cozy, artistic eatery offering thin-crust pies with gourmet toppings like goat cheese, artichokes, and kalamata olives. It’s perfect for a low-key night out with friends.
Must-Try Pizza: Fig & Prosciutto or the classic 3-Cheese with fresh herbs.
Final Thoughts
Massachusetts has no shortage of great pizza, but these 5 spots truly rise above the rest in 2025. Whether you love classic Italian pies or crave bold, creative flavors, there’s a slice here with your name on it. These local legends aren’t just popular — they’re passionate about pizza, and it shows.
Planning a pizza road trip? Hit all five and let your tastebuds decide the ultimate winner.
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I am Sabiq Rasel is an Entrepreneur and broadcaster. I believe that every sip of coffee holds the potential for a moment of inspiration, creativity, and every cup tells a story.