When it comes to top-tier healthcare in the Midwest, Minnesota is home to some of the most respected hospitals in the country. Whether you’re a resident or visiting for treatment, knowing where to go for excellent patient care can make all the difference. This 2025 guide highlights the top 10 best hospitals in Minnesota, based on real patient reviews, clinical excellence, and overall reputation. From world-renowned institutions to community-based medical centers delivering compassionate care, these hospitals have earned their place through years of trust and outstanding service.
1. Mayo Clinic – Rochester, MN

Rating: ⭐ 4.9/5 (Thousands of patient reviews)
Specialties: Cancer, Cardiology, Neurology, Transplants
If you’re researching the best hospitals in Minnesota, there’s no way to leave out Mayo Clinic in Rochester. Consistently ranked as the #1 hospital in the U.S. by U.S. News & World Report, Mayo is a global leader in research-driven, patient-first care.
Why patients love it:
Personalized treatment plans
Access to cutting-edge clinical trials
Empathetic and highly skilled physicians
Clean, modern facilities and short wait times
Mayo Clinic is especially known for its world-class cancer treatment, neurology, and organ transplant programs. International patients also frequently travel to Mayo for complex diagnoses.
2. Abbott Northwestern Hospital – Minneapolis, MN

Rating: ⭐ 4.7/5
Specialties: Heart care, Stroke, Orthopedics, Neuroscience
Abbott Northwestern Hospital is the flagship facility of Allina Health and stands out for its exceptional cardiovascular and neurological care. Located in the heart of Minneapolis, it’s one of the busiest and most trusted hospitals in the state.
What makes it exceptional:
Leading stroke center in Minnesota
Advanced robotic surgery and orthopedic care
Strong emphasis on integrative medicine and patient education
Patients consistently praise the professional staff, clear communication, and efficiency of emergency services. Abbott also excels in handling complex procedures with short recovery times.
3. Essentia Health – St. Mary’s Medical Center, Duluth, MN

Rating: ⭐ 4.6/5
Specialties: Cancer, Trauma, Pediatrics, Internal Medicine
Serving northern Minnesota and neighboring states, Essentia Health – St. Mary’s Medical Center in Duluth is a full-service, Level I Trauma Center known for holistic, community-focused care.
Key strengths:
Extensive cancer care and support services
Pediatric intensive care unit (PICU)
Mental health and addiction treatment programs
Reviewers often highlight the kindness of the nursing staff, the hospital’s commitment to patient dignity, and the focus on emotional well-being, especially for families going through difficult diagnoses.
4. M Health Fairview University of Minnesota Medical Center – Minneapolis, MN

Rating: ⭐ 4.5/5
Specialties: Organ transplants, Cancer, Rare disease research, Psychiatry
M Health Fairview University of Minnesota Medical Center combines academic research with compassionate patient care. As a teaching hospital tied to the University of Minnesota, it plays a critical role in advancing medical research and education.
Why it ranks in the top 5:
Offers one of the top transplant programs in the Midwest
Strong psychiatric services and adolescent mental health
Patients often receive early access to clinical innovations
It’s especially favored by patients with rare or complex illnesses who need a multidisciplinary team. Many mention the hospital’s transparent communication and shared decision-making approach.
5. CentraCare – St. Cloud Hospital, St. Cloud, MN

Rating: ⭐ 4.4/5
Specialties: Cardiology, Women’s Health, Pediatrics, Rehabilitation
St. Cloud Hospital is the largest regional medical center in central Minnesota and part of the CentraCare health system. It’s frequently rated highly for its patient-centered care, especially in maternity, pediatric services, and heart care.
Highlights:
NICU with high survival rates
Accredited Chest Pain Center
Comprehensive rehabilitation services
Families and patients appreciate the hospital’s comfort-first approach, including private birthing suites, friendly bedside manner, and ease of scheduling follow-ups.
6. Children’s Minnesota – Minneapolis & St. Paul

Rating: ⭐ 4.8/5
Specialties: Pediatric Care, Neonatology, Pediatric Surgery, Specialty Clinics
Children’s Minnesota is the leading pediatric healthcare provider in the state, dedicated exclusively to children’s health. Serving the Twin Cities area, it’s consistently rated one of the best children’s hospitals in the Midwest.
Why families trust Children’s Minnesota:
Comprehensive specialty clinics for rare childhood conditions
Level IV Neonatal Intensive Care Unit (NICU)
Child-friendly environment with playrooms and family support services
Parents frequently praise the staff’s compassion and patience, the hospital’s focus on mental and emotional health for kids, and their seamless coordination with schools and community programs.
7. Regions Hospital – St. Paul, MN

Rating: ⭐ 4.5/5
Specialties: Trauma, Cardiology, Neuroscience, Emergency Medicine
Regions Hospital is the largest Level I Trauma Center in Minnesota and plays a critical role in emergency and specialized care for the St. Paul area.
Patient highlights:
Fast and expert emergency response teams
Advanced heart and stroke care units
Strong rehabilitation and physical therapy programs
Patients appreciate Regions for its emergency preparedness, clear communication during critical moments, and comprehensive post-discharge support to help recovery.
8. Fairview Southdale Hospital – Edina, MN

Rating: ⭐ 4.4/5
Specialties: Women’s Health, Orthopedics, Cardiac Care, Outpatient Surgery
Serving the southwestern Minneapolis metro area, Fairview Southdale Hospital is known for its strong focus on women’s health services and minimally invasive surgical procedures.
What patients say:
Exceptional maternity and birthing care
Friendly staff and smooth outpatient surgery experiences
Emphasis on pain management and comfort
It’s a popular choice for families and individuals looking for accessible, high-quality care without the hustle of a major urban hospital.
9. Gundersen Health System – La Crosse, WI (Serving Southeast Minnesota)

Rating: ⭐ 4.5/5
Specialties: Cancer, Heart & Vascular, Primary Care, Orthopedics
While technically located in Wisconsin, Gundersen Health System serves many patients in southeastern Minnesota and is often chosen for its comprehensive and community-based approach.
Key benefits:
Patient-centered care with extensive support programs
Strong cancer treatment and heart care facilities
Integration of mental health and physical health services
Patients commend Gundersen’s personalized care plans, local access to specialists, and commitment to rural healthcare access.
10. North Memorial Health Hospital – Robbinsdale, MN

Rating: ⭐ 4.3/5
Specialties: Emergency Medicine, Cardiology, Orthopedics, Neurosurgery
North Memorial Health Hospital is well-known for its fast and efficient emergency services and critical care. Serving the northwest suburbs of Minneapolis, it’s a vital resource for urgent health needs.
What stands out:
Level II trauma center with a quick response time
Comprehensive cardiac care and rehabilitation
Patient-first approach in critical care units
Reviewers highlight the attentiveness of the medical teams, cleanliness of the facility, and clear communication during stressful emergencies.
Final Thoughts: Choosing the Right Hospital in Minnesota
Every hospital on this list offers something unique—whether it’s globally recognized specialists or a focus on community and wellness. Your choice will depend on what matters most: convenience, a specific treatment, or long-term care.
If you’re dealing with a serious health issue, we highly recommend starting with Mayo Clinic in Rochester due to its unmatched level of care. But for most needs, the rest of these hospitals provide exceptional services that rival any top-tier facility nationwide.
Frequently Asked Questions (FAQs)
Q1: How do I choose the best hospital in Minnesota for my needs?
Look for hospitals with specialties related to your condition, check patient reviews, insurance coverage, and ask your primary care doctor for recommendations.
Q2: Are these hospitals covered by most insurance plans?
Most top Minnesota hospitals accept a wide range of insurance plans, but it’s best to verify with your insurer before scheduling treatment.
Q3: Can I get a second opinion at these hospitals?
Yes, many of these hospitals encourage second opinions and offer consultations with specialists to ensure the best care plan.
Q4: Do these hospitals offer emergency services?
Yes, all hospitals listed provide emergency care, with several designated as Level I or Level II Trauma Centers for severe cases.
Q5: How do I prepare for my hospital visit?
Bring your insurance info, medical records, a list of medications, and prepare questions for your doctor. Arrive early and follow any pre-appointment instructions.
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I am Sabiq Rasel is an Entrepreneur and broadcaster. I believe that every sip of coffee holds the potential for a moment of inspiration, creativity, and every cup tells a story.